Gastric cancer generally has the process of metaplasia, and intestinal metaplasia is the precancerous lesion of gastric cancer. The evolution of gastric malignant tumor from intestinal metaplasia, firstly, evolves from normal gastric mucosa to chronic superficial gastritis, then develops into chronic atrophic gastritis, and appears incomplete small intestinal metaplasia to incomplete large intestinal metaplasia and then heterogeneous hyperplasia, which manifests itself in the early stage of gastric cancer, then develops into the progressive stage of gastric cancer. The development of malignant tumors in the stomach is determined by a combination of factors, often the presence of genetic factors, Helicobacter pylori infection, smoking, alcohol consumption, environmental factors and so on. However, the probability of intestinal metaplasia evolving into a malignant tumor is still relatively low, about less than 5%. When intestinal metaplasia occurs, it is necessary to pay attention to regular gastroscopy to determine the evolution of the gastric mucosa. For patients with intestinal metaplasia, it is recommended to consult the gastroenterology department of regular hospitals and undergo regular gastroscopy to avoid delays.