Infants and children with acute necrotizing enterocolitis have atypical symptoms, with the onset of the disease in the first 3 to 10 days of life. They are admitted to the ward due to prematurity or low weight, and during artificial feeding or during nasal feeding with a gastric tube placed in immature children due to incomplete establishment of the swallowing reflex, they are found to have retention in the stomach, followed by abdominal distention, vomiting, blood in the stool fever or temperature not rising, tachycardia or slow heart rate, abdominal muscle tension, abdominal distension, and erythema of the abdominal wall. What are the diseases that are easily confused? 1, intussusception The onset of childhood is easily misdiagnosed as intussusception, but generally intussusception is manifested as paroxysmal abdominal colic, intermittent episodes lasting several minutes each time, remission period children play as usual, in abdominal pain episodes can often be found in the right lower abdomen intestinal wall mass, anal examination can be seen finger stained with blood without special fishy smell, for cases of ileocolic intussusception often appear in early jam-like stool, but small intestine type intussusception occurs later blood in stool. 2, allergic purpura Allergic purpura is a metabolic disease, mainly involving the capillary wall and bleeding symptoms, for intestinal reactions are mostly caused by intestinal mucosal edema, bleeding, clinical manifestations of sudden onset of abdominal colic, mostly located around the umbilicus and lower abdomen, sometimes very violent, but can be accompanied by skin purple spot, joint swelling and pain, urine examination can be found protein urine, hematuria or tubular urine. 3, strangulated mechanical intestinal obstruction for complete intestinal obstruction, X-ray standing plain film can be seen in the plane of high tension intestinal gas and colonic airless, different from the X-ray signs of enterocolitis. Crohn’s disease is a chronic recurrent inflammatory disease of the gastrointestinal tract, with pathological changes in addition to eosinophil, plasma cell and lymphocyte infiltration, and granuloma-like changes, which can form intestinal luminal strictures, internal fistulas and adhesions. 5.Other AHNE should be differentiated from acute appendicitis, acute enteritis, bacillary dysentery, Mechel diverticulitis, Crohn’s disease, mesenteric vascular embolism, intestinal ascariasis, biliary ascariasis, etc.