Atrial septal defect is a common congenital heart disease, intervention and open heart surgery are both commonly used for the treatment of atrial septal defect, intervention is a minimally invasive surgery so less traumatic, while open heart surgery is a traditional surgical method, the efficacy of the treatment is accurate, but trauma is greater and the risk is higher. 1. Interventional surgery: Advantages: intervention is minimally invasive surgery, mainly to exclude other complex malformations, strict control of the indications, can be used to catheterize interventional blockage treatment. Because there is no need to open the chest, it is not easy to be injured, less painful, short hospitalization time, safe and reliable. Disadvantages: Compared with open chest surgery, there are certain advantages, high technical success rate, fast recovery of cardiac function after surgery, but there are certain limitations of the surgery. 2. Open chest surgery: Advantages: belongs to the traditional surgical method. Repair treatment through open chest requires repairing mitral valve cleft under extracorporeal circulation and repairing atrial septal defect with patch. Disadvantages: the efficacy is exact, but the surgical risk is higher, trauma is greater, and the recovery time is longer. When patients find atrial septal defects, they should go to regular hospitals in time, and the specialized doctors will choose the appropriate method according to the specific condition of the patients.