Cranial repair is a relatively routine procedure in neurosurgery to repair skull defects caused by traumatic brain injury and craniotomy. Some patients ask how skull repair is done. In fact, after a long period of development and progress, skull repair technology has been very mature and the specific operation is not difficult, but mainly lies in the selection of repair materials. Let’s take a look at how to do skull repair and then discuss the choice of repair materials. Generally, it takes about 3 months to recover from a skull defect, and then the repair is performed. In the surgery, the scalp is cut open, the periosteum is bluntly separated, the bone window is completely exposed, the repair prosthesis is taken and placed in the bone window, and adjusted to achieve physiological anatomical repositioning, and the skin is sutured layer by layer. The surgical implementation is not difficult, but mainly lies in the application of good repair materials. There are still some problems with the titanium mesh material widely used in clinical practice, such as the possibility of rejection, complications, chronic postoperative cutting pain, sensitivity to heat and cold, etc., which can also affect future CT, MRI and other medical examinations. PEEK is an ideal material for cranial repair because of its biocompatibility, three-dimensional shaping, precise fit to the defect area, and excellent elasticity, insulation, stability, and strength.