A 48-year-old woman who has not had her period for two months may be related to perimenopause, pregnancy, endocrine disorders, other diseases and other reasons. 1. Perimenopause: 48-year-old women may enter perimenopause due to the decline of ovarian function and the decrease of estrogen secretion, the menstrual cycle is no longer regular, which is a normal physiological phenomenon, no need to be nervous. 2. Pregnancy: If a 48-year-old woman’s menstrual cycle has been more regular and she can ovulate, there is still a possibility of pregnancy after sex, and she won’t have her period after pregnancy. 3. Endocrine disorders: If a woman has poor sleep quality, excessive stress and nervousness in the recent past, it will easily lead to endocrine disorders and she will not have her period. 4. Other diseases: abnormal thyroid function, pituitary prolactinoma, hypoadrenalism and so on can lead to amenorrhea. There are many reasons why a 48-year-old woman does not have menstruation for two months, so it is recommended to go to the hospital for a relevant examination to clarify the cause and then treat it.