The enlarged lymph node in the right iliac vessel area is considered to be caused by infection, reactive hyperplasia, tumor metastasis and so on. 1. Infection: the enlarged lymph nodes are mainly caused by pathogenic infection, such as bacteria, viruses and so on. Enlarged lymph nodes in the right iliac vessel area can be caused by right pelvic and abdominal infections, such as abdominal abscess, adnexitis, acute suppurative appendicitis and so on. 2. Reactive hyperplasia: some systemic diseases can lead to reactive hyperplasia of local lymph nodes, which is manifested as enlarged lymph nodes, for example, systemic lupus erythematosus, necrotizing hyperplastic lymph nodes and so on. 3. Tumor metastasis: especially malignant tumor metastasis will cause lymph node enlargement in corresponding parts, and lymph node enlargement in right iliac vascular region is mostly caused by lymphatic metastasis of right hemi-colon cancer, ovarian cancer, rectal cancer and other cancers. It is recommended to go to the hospital in time to find out the cause of enlarged lymph nodes in the right iliac vessel area.