Blisters on the liver are usually considered localized liver cysts. A liver cyst is a cystic lesion of the liver, which may contain a certain amount of fluid, hence the dark areas of fluid show up as blisters on ultrasound. Liver cysts are a common benign liver lesion, usually small in size and without obvious symptoms, and do not require treatment; regular review is recommended. Individuals with huge liver cysts or liver cysts with complications, such as hemorrhage and infection within the cysts, can lead to fever, pain and other symptoms. In this case, puncture drainage should be used for treatment. Some liver cysts require surgical removal, which can be done by laparoscopic opening. Patients with blisters on the liver need to go to the hospital in time to get a clear diagnosis and targeted treatment under the guidance of a professional physician.