Hypofractionated squamous carcinoma is only a histopathological classification and is not definitively advanced, but may be intermediate or early intermediate. However, most of the hypofractionated squamous carcinomas like this one are more malignant and are more common in advanced stages. Generally speaking, hypofractionated squamous carcinoma also depends on the location, for example, it is possible to have hypofractionated squamous carcinoma in esophagus, nasopharynx, cervix and lung. The treatment method differs from site to site. If surgical treatment is possible, the treatment plan of radical surgery with adjuvant chemotherapy can be adopted. If surgery is not possible or if the disease is too advanced to be operated, radiotherapy can be considered in this case.