The causes of pain and weakness in the hands and feet are as follows: 1, due to cerebrovascular accidents and other diseases, cerebrovascular accidents, many patients will have weakness in the hands and feet, quadriplegia, such as cerebral infarction or cerebral hemorrhage patients often have similar symptoms, in the hospital through the cranial CT or MRI can be a clear diagnosis. 2, may be suffering from chronic diseases and calcium deficiency and other factors, such as diabetes, hypertension and osteoporosis and other diseases, many patients will show symptoms of weakness and mental fatigue. For example, after suffering from diabetes, high blood pressure and osteoporosis, many patients will show symptoms such as weakness of hands and feet, mental fatigue, etc. 3, may also be due to exertion and other reasons, when overworked, there will be weakness of the hands and feet, fatigue, lazy, through a short period of time to rest and recovery can be improved.