Hepatic encephalopathy, also commonly known as hepatic coma, is caused by severe liver disease and mainly manifests as altered consciousness, such as coma, mental disturbance, hallucinations and hallucinations. The main treatment is to remove the triggers of hepatic encephalopathy attacks and adjust the diet structure. We should control the intake of protein and soy products, correct the disorders of water and electrolytes, and acid-base balance, and some patients may have blood accumulation in the intestinal tract of the digestive tract. For medication, lactulose can be used, which prevents the production and absorption of ammonia in the intestine. Oral antibiotics such as metronidazole, neomycin, and antibiotics can be administered. There is inhibition of intestinal urease production, oral administration of certain beneficial bacteria that do not produce urease to promote the metabolism of ammonia in the body, and also liver-protective preparations, as well as other treatments, routine treatment of the liver. Liver transplantation is an effective means of treating end-stage liver disease, to reduce brain oxygen consumption and protect the function of brain cells.