There is no exact research on how much influence of cancer hereditary gene has now, but patients with family history of malignant tumors have higher incidence rate than the general population and need regular medical checkups.
Cancer is malignant tumor. Current scientific research points out that there is a tendency of family aggregation in the development of malignant tumors, i.e., after the development of a certain malignant tumor in a family, the risk of other members to develop that malignant tumor will increase, which proves that genetic inheritance has an influence on the development of cancer.
Due to the individualized differences in patients’ conditions, the exact extent of genetic influence among different patients is still unclear.
With the continuous development of medicine, the genetic susceptibility genes of some malignant tumors have been discovered one after another.
For example, the development of endometrial cancer patients is often closely related to the overexpression of HER2 gene, PTEN gene mutation, p53 gene mutation and so on.
The pathogenesis of patients with hereditary nonpolyposis colorectal cancer syndrome is mostly associated with mismatch repair gene mutations.
The development of ovarian cancer patients is associated with BRCA1 and BRCA2 gene mutations.
Patients with hereditary cancer genes should undergo regular medical checkups so that abnormalities can be detected as early as possible for timely treatment and improved prognosis.