Taking antihypertensive drugs to develop a large pressure difference, which in turn leads to dizziness is recommended to seek prompt medical attention. According to the severity and cause of the disease to determine whether to change the drug, and pay attention to adjust the lifestyle. Under normal circumstances, the differential pressure fluctuates within the range of 30~40mmHg, and in the elderly, it may increase to 30~60mmHg. When the differential pressure is greater than 60mmHg, it is called increased differential pressure. If the differential pressure increases after taking medication, it is recommended to consult a doctor in time and complete relevant examinations to determine the cause of the increase in differential pressure. Usually, atherosclerosis in the elderly may lead to increased pressure difference after taking antihypertensive drugs, or it may simply be caused by the side effects of the drugs, such as increased pressure difference or dizziness. Depending on the patient’s condition, the use of lipid-regulating drugs, such as simvastatin or etorvastatin, etc., may be appropriate. Patients with more pronounced increase in blood pressure difference should change the type of antihypertensive drugs, and can choose angiotensin-converting enzyme inhibitors and other drugs with fewer side effects, such as captopril, enalapril, etc.. The specific treatment program should follow the doctor’s instructions. Patients should also pay attention to a low-salt and low-fat diet, try to avoid eating animal offal, quit smoking and drinking, and maintain a suitable amount of exercise. Changes in lifestyle habits can alleviate the increase in differential pressure to a certain extent.