The first step in the detection of a novel coronavirus is to draw blood for routine blood tests. Early on, the total white blood cell count may be normal or decreased, and the lymphocyte count may be decreased. Biochemistry may include elevated transaminases, creatine kinase, elevated C-reactive protein, and elevated D-dimers. Next, imaging may be performed. The early stage may show multiple small patchy shadows and interstitial changes, which are obvious in the outer lung zone, and then develop into multiple ground glass-like infiltrates in both lungs, and in severe cases, solid lung changes may occur, but pleural effusion is rare. In addition, special tests can be performed, including detection of pathogens and collection of pharyngeal swabs, sputum or specimens of lower respiratory secretions for nucleic acid testing of novel coronaviruses.