Persistent pain in the anterior region of the heart is an abnormal symptom, it is recommended that patients go to the regular hospital to check first, which may be the manifestation of certain diseases, such as coronary heart disease, costochondritis, pleurisy and so on. 1. Coronary heart disease: some patients may have no obvious symptoms, symptoms often manifested as chest pain (angina), palpitations, shortness of breath, often triggered by physical labor, emotional excitement, satiety, cold, smoking and so on. 2. Costochondritis: The costochondritis in the chest is single or multiple elevations, mostly unilateral, but also bilateral. Usually there are localized pains of varying severity and nature, which can be dull or sharp, and the pain is obvious when pressed. 3. Pleurisy: the most common manifestation is chest pain, usually occurring only on the same side of the pleurisy, the pain can persist, can be aggravated during deep breathing; when restricting respiratory exercise, there can also be chest tightness, shortness of breath, dyspnea and other symptoms. However, this symptom alone is not enough to diagnose the disease, and there may be other factors causing it. Therefore, it is recommended that the patient consult a doctor in time to clarify the cause of the disease and give targeted treatment.