Botulinum toxin refers to botulinum toxin, if improper use of botulinum toxin is prone to cause muscle atrophy, nerve damage and other hazards, may also cause allergies. General reasonable use is not obvious harm. The essence of botulinum toxin is neurotoxin, the mechanism of action is to inhibit the release of acetylcholine from nerve endings. If there is inappropriate injection of botulinum toxin, such as a single dose of too much, too frequent injection, etc., to a certain extent, it is easy to lead to muscle strength loss, causing muscle atrophy, muscle weakness can occur. In addition, it is also easy to damage the nerves, resulting in nerve numbness, and in severe cases, it is easy to cause permanent paralysis, which can be manifested as dull facial expression, abnormal sensation and so on. Secondly, some people who are allergic to botulinum toxin will have allergic symptoms such as itching and erythema after botulinum toxin injection. However, under normal circumstances, normal and reasonable use of botulinum toxin is not too harmful to the body. All in all, we must standardize the inoculation of Botox in regular hospitals, and if there is any discomfort, we need to go to the hospital in time.