Eat expectorants such as Ambroxol and Acetylcysteine for sputum after early lung cancer surgery, and antibiotics such as Azithromycin and Amoxicillin if coughing up sputum caused by bacterial infection. Lung cancer is a common malignant tumor disease of respiratory system. Expectoration after early lung cancer surgery is one of the common surgical complications. Usually, patients need to take expectorant drugs under doctor’s guidance, such as Ambroxol, Acetylcysteine, Hydroxymetholestyramine, Bromhexine, etc., which can reduce the viscosity of sputum to a certain extent and increase the clearing ability of respiratory tract cilia. Besides, if the patient coughs up yellowish green sputum after early lung cancer surgery, it is mostly considered to be caused by secondary bacterial infection, and the patient also needs to take or drip azithromycin, amoxicillin, cefazolin and other antibiotics according to the doctor’s instruction. In addition to oral drug treatment, patients with excessive sputum can also undergo nebulization treatment or sputum aspiration. To summarize, patients with excessive sputum after early lung cancer surgery need to actively cooperate with doctors for treatment and strengthen oral hygiene care to prevent affecting postoperative physical recovery. Please strictly follow the doctor’s prescription for medication, and do not use medication on your own.