There are differences between malignant and benign thyroid nodules in terms of clinical manifestations, imaging manifestations and prognosis. 1. Clinical manifestations: benign thyroid nodules usually have no obvious clinical symptoms, but when the nodules are large, they may cause esophageal compression and dysphagia. In addition to the above symptoms, malignant thyroid nodules may invade the recurrent laryngeal nerve and cause hoarseness, and invade the trachea and cause dyspnea and hemoptysis. 2. Imaging performance: benign thyroid nodules generally have a more uniform density and less calcification. Malignant thyroid nodules usually have unclear margins and borders, or even blurred, with uneven density and calcification. 3. Prognosis: benign thyroid nodules generally do not affect the survival of patients, while malignant thyroid nodules have the risk of infiltration and metastasis, which can shorten the survival of patients. Patients who are detected with thyroid nodules should go to the hospital in time, improve the examination, clarify the nature of the nodules and then treat them in time. If you feel unwell, please seek medical advice promptly.