There are many causes of pain between the eyebrows, including inflammation, fatigue, etc., as follows: 1, inflammation: acute inflammation of the eye, such as glaucoma, acute attacks of glaucoma will also show pain between the eyebrows, a sore feeling, accompanied by loss of vision, increased intraocular pressure and other performance, inflammation of the ear, nose and throat, such as sinusitis, will also show the feeling of pain between the eyebrows. Inflammation of the skin between the eyebrows and the soft tissues under it can cause stinging pain while showing redness and swelling of the skin.2. Fatigue: like visual fatigue, that is, prolonged late night and fatigue, can also show soreness between the eyebrows or at the root of the nose.3. Other: lesions of the surrounding tissues, such as sinusitis, can also cause pain between the eyebrows. Therefore, there are many reasons for pain between the eyebrows, and specific examination is needed to determine the cause and then to treat the symptoms.