Relationship Between Chronic Obstructive Lung and Asthma The definition of chronic obstructive lung and the new understanding of asthma increasingly suggest that chronic obstructive lung is very similar to chronic persistent asthma. Certain asthmatics can have mixed or irreversible airflow obstruction, making it impossible to make a clear distinction between asthma, in which airflow obstruction is not fully reversible, and chronic bronchitis and emphysema, in which airflow obstruction is partially reversible. I. Similarities: Chronic obstructive pulmonary disease and bronchial asthma are both obstructive airway diseases, and the main common or similar points of the two are: 1, both have chronic inflammation of the airways; 2, both have a genetic basis and the role of environmental factors in the background; 3, both have the pathophysiological abnormalities of bronchial spasm and hypersecretion; 4, both can manifest dyspnea, chest tightness, breathlessness, wheezing, coughing; 5, some of the patients with chronic obstructive pulmonary disease may manifest airway hyperresponsiveness; 6, some of the patients with chronic obstructive pulmonary disease may manifest airway hypersecretion; 7, some of the patients with chronic obstructive pulmonary disease may manifest airway hypersecretion. Inhaled glucocorticosteroids and long-acting bronchodilators are effective in moderate-to-severe persistent asthma and chronic obstructive pulmonary disease, especially when they are combined in the same inhalation device, which further proves that there is indeed a similarity in the nature of the lesions of chronic obstructive pulmonary disease and asthma. Differences: There are many differences between chronic obstructive pulmonary disease (COPD) and asthma, the most important of which are as follows: 1, asthma has an early onset, starting in infancy and early childhood, while COPD usually starts after middle age, and most of them are smokers or people exposed to hazardous gases or particles, and most of the symptoms are very typical and lung function is significantly impaired in the old age; 2, asthma is obviously familial, reflecting the close relationship between asthma and genetics, and COPD has a strong genetic relationship with asthma. Although chronic obstructive pulmonary disease (COPD) also has a family distribution, it is mostly related to the same smoking habit or environment, which is difficult to be explained by genetic susceptibility; 3. Most patients with asthma suffer from other allergic diseases, especially allergic rhinitis and dermatitis (e.g., eczema), whereas the probability of COPD patients suffering from these allergic diseases is very low; 4. Airway provocation and diastolic tests show that bronchial tubes of patients with asthma are characterized by a high degree of allergy. 4. Airway provocation and diastolic tests show that the bronchial tubes of asthmatics are markedly constrictible and diastolic, whereas the response of patients with chronic obstructive pulmonary disease (COPD) to these tests is usually weak; 5. Asthma onset or exacerbation is episodic, cyclic, and seasonal, and can be relieved on its own or by treatment, whereas COPD patients have basically persistent and progressive symptoms, and it is the main cause of disease, death, and depletion of health care resources globally, with 275,000 deaths due to COPD each year. It is the leading cause of disease, death and depletion of health care resources worldwide, with approximately 2.75 million deaths attributed to COP each year.