Hepatitis B DNA can drop on its own in some patients without medication. The natural course of hepatitis B is usually divided into the immune tolerance phase of hepatitis B, the immune clearance phase, then the immune stabilization of hepatitis B, i.e. inactive hepatitis B, and the fourth phase is the reactivation phase. In the immune clearance phase of hepatitis B, hepatitis B DNA and hepatitis B viral load will automatically decrease, then accompanied by some mild impairment of liver function. Therefore, hepatitis B virus carriers can not easily carry out antiviral treatment, must be in line with the premise of antiviral treatment indications, and can not be antiviral treatment in the hepatitis B immune tolerance period. In the immune clearance period of hepatitis B, most patients can complete this process by themselves, and those who do not meet the conditions for antiviral treatment are also unable to do antiviral treatment.