No nap on the headache is mostly seen in patients who have a regular nap habit for a long time, but also in anxiety, depression, insomnia, migraine, cerebrovascular disease, etc.. Long-term napping habits of patients due to the biological clock has been formed, suddenly do not nap will appear plant nerve dysfunction resulting in the occurrence of headaches. This situation is generally temporary reversible, adjust the habits of rest and relaxation after the symptoms can disappear. Patients with anxiety and depression can be accompanied by depressed mood, irritability, disinterest in things around them, mostly seen in young and middle-aged women. Migraine is often induced by poor rest at lunchtime. Patients show fluctuating headache with blood vessels near one or both temples, which may be accompanied by nausea, vomiting and blurred vision. Cerebrovascular disease is mostly seen in middle-aged and elderly patients, often with weakness of the limbs, sensory impairment, distorted mouth and eyes, and difficulty in swallowing. Headache should be treated promptly and, if necessary, a CT or MRI of the head should be performed to exclude intracranial organic disease.