Stroke is the first cause of death in China, and among stroke subtypes, ischemic stroke is the most common. Dyslipidemia is an important risk factor for ischemic stroke or transient ischemic attack (TIA), and strengthening lipid management plays an important role in both preventing stroke occurrence or reducing recurrence. Here we review the requirements of the latest stroke guidelines for lipid management in 2015. 1. Acute lipid management: Studies have shown that early use of statins is an independent predictor of improved prognosis in patients with acute ischemic stroke. Acute phase statin therapy also improves early and 1-year neurological prognosis. Increasing the statin dose further improved survival and neurological prognosis. Therefore, the Chinese guideline for lipid management in ischemic stroke recommends statin therapy in the acute phase. There is a significant correlation between dyslipidemia and the incidence of ischemic stroke. Studies have shown that for every 1 mmol/L increase in total cholesterol, the incidence of stroke can increase by 25%. This guideline recommends the following for lipid management in primary prevention of stroke. 3. Lipid management in secondary prevention: Cholesterol levels are an important factor in the recurrence of ischemic stroke or TIA. Lowering cholesterol levels can reduce the occurrence, recurrence and death of ischemic stroke or TIA. The clinical benefit of intensive cholesterol lowering for stroke prevention has been confirmed by clinical studies.