Drooling in the elderly may be caused by oral diseases, cardiovascular diseases, or other diseases. Anti-infective, statin drugs or through other ways of treatment can be given according to different diseases. 1. Oral diseases: Older people with oral diseases, such as gingivitis, oral ulcers, pharyngitis, oral tumors, denture stimulation may lead to drooling. It is recommended to go to the hospital stomatology department. If it is caused by infection, cephalosporin or amoxicillin can be given to control the infection. If it is dental caries, it is recommended to fill the tooth for treatment. Oral tumor can be considered surgical resection treatment. 2. Cardiovascular and cerebrovascular diseases: For cardiovascular and cerebrovascular diseases, such as cerebral embolism and cerebral infarction, statins, such as atorvastatin, can be given under the guidance of the doctor to prevent thrombosis. 3. Other diseases: Parkinson’s disease causes drooling, it is recommended to pay attention to the intervention of lifestyle habits, and if necessary, give Benzhexol hydrochloride for treatment. Alzheimer’s disease causes drooling, if there is depression, can give doxepin, maprotiline and other drugs to regulate. Neuromodulation disorders leading to drooling can be treated with medications such as vitamin B1, ghrelin, and paroxetine hydrochloride. Drooling in the elderly is related to a variety of factors, it is recommended to take the elderly to the hospital stomatology, general internal medicine for examination, first to find the cause, and then for the cause of the disease, under the guidance of the doctor to use medication.