The vast majority of patients with chronic nephritis will not turn into uremia. Nephrologists often find that some patients feel good about themselves, but when they go to the hospital for relevant examinations, they already have uremia. At the same time, we can also see patients with minor urine test abnormalities, even if they do not take drugs, kidney function can be stabilized for a long time. In addition, we can also see patients who have more urinary protein but with good management, their renal function can be stabilized for a long time. Although the above three different groups are all suffering from chronic nephritis, the outcome of the disease is very different. Chronic nephritis from just found to the development of uremia, related to the following aspects; 1, urine protein control: no matter early or advanced chronic kidney disease, the higher the amount of urine protein, the shorter the time of renal progression; 2, blood pressure control: with the progression of renal function, there can be elevated blood pressure, and elevated blood pressure will also accelerate the deterioration of renal function, the general requirement of chronic nephritis blood pressure is controlled at 130-80mmHg below, but the At present, the number of people who reach the standard is less than 10%; 3, the beginning of the discovery of the level of renal function: kidney disease is very important that early prevention and treatment is needed, so creatinine level at the time of discovery can also affect the prognosis; 4, anemia: if hemoglobin is below 10.5g/L for a long period of time, that is, it will be easy to develop into end-stage renal failure; 5, high-protein, high-salt diet: irregular lifestyle, often binge drinking and overeating will be detrimental to the health of the; 6, infections and exertion Factors: can lead to stabilize kidney disease again activity, accelerate the speed of renal failure; 7, treatment compliance: chronic nephritis patients need long-term management, irregular medication, not timely review of the often poor results. Therefore, old age, sickness and death are the norm of life, even if the technology is so developed, only a few of them can really cure the disease completely, learn to tolerate and understand the survival of the disease, and set up a good mentality, in order to become a happy person.