There are several reasons for the swelling of the upper lip after waking up from a nap: First, it is due to traumatic edema caused by inadvertently pressing the hand or heavy object on the upper lip while sleeping, and this condition often has obvious traces of pressure injury. The swelling can be quickly reduced by taking oral blood-stasis-boosting medicine and rest. Second, the swelling of the upper lip after waking up may be caused by mosquito bites. As a result of mosquitoes and insect bites while sleeping, you will find that the upper lip is swollen, numb, painful and itchy after waking up, and you will be able to see the traces of mosquito bites upon closer inspection. You can apply wind oil, cool oil can be very good to reduce swelling. Third, the swelling of the upper lip when waking up from sleep may be idiopathic angioneurotic edema. This disease is often due to low autoimmunity, due to a dry environment or other reasons, will make the upper lip vascular permeability increases, will appear swelling phenomenon. This situation does not need special treatment, a little rest will reduce the swelling, and will not leave any serious sequelae, do not worry too much.