There is no specific disease of speech disorder in medicine. Symptoms of speech disorder can be seen in a variety of diseases, and the specific treatment drugs need to be selected according to the primary disease, and the commonly used drugs include antibiotics, antipsychotics, and so on. Commonly used drugs include antibiotics, antipsychotics, etc. Common primary diseases for speech disorder symptoms include physical diseases such as purulent meningitis and recurrent otitis media, mental diseases such as autism and stuttering, and special conditions such as lead poisoning. Different diseases have their own targeted therapeutic drugs. 1. Purulent meningitis drugs: ① antibiotics: penicillin, ceftriaxone, etc., according to the pathogenic bacteria need to choose the appropriate sensitive drugs; ② glucocorticoids: such as dexamethasone, mainly used for the more serious condition. 2. Recurrent otitis media drugs: ① antibiotics: erythromycin, cefuroxime, etc.; ② non-steroidal anti-inflammatory drugs: acetaminophen, aspirin, etc.; ③ ethanol preparations: ethyl glycerol boric acid, chloramphenicol glycerol, etc., used for pus to reduce the ear drops. 3. Autism drugs: ① new antipsychotics: risperidone, aripiprazole, etc.; ② attention deficit hyperactivity disorder treatment drugs: methylphenidate, atomoxetine, etc.; ③ antidepressants: sertraline, paroxetine and so on. However, it should be noted that there is no specific drug for the core symptoms of autism, and the above drugs are only used for symptomatic treatment. 4. Stuttering medication: anxiolytics such as eszopiclone and buspirone are suitable for those with obvious anxiety. To summarize, people with speech disorders should consult a doctor to find out the cause of the disorder, and then take medication under the doctor’s guidance, and some of the diseases need other treatment measures in addition to medication in order to strive for a good prognosis.