Atrial fibrillation can lead to death because the atria lose their normal pumping function in atrial fibrillation, and the blood in the atria stagnates after atrial fibrillation, and the blood flows very slowly, making it easy for blood clots to form in the atria. The embolus is more likely to lead to arterial embolism after dislodgement, and the most common one is cerebral artery embolism, i.e. stroke. Stroke is the biggest danger of atrial fibrillation, the incidence of stroke in atrial fibrillation patients is 5 or 6 times higher than normal, and the incidence of stroke in valvular atrial fibrillation is 17 times higher than normal, so atrial fibrillation patients have the most serious consequences of stroke, the larger the stroke area, the more brain death will occur, which is more likely to lead to death. Five patients will have a stroke each year, so it is important to follow your doctor’s advice and take antithrombotic drugs. Patients with atrial fibrillation are most often treated with anticoagulant drugs, commonly warfarin, and it is important to monitor the international normalized ratio in the blood while taking warfarin, which is within a reasonable range to prevent stroke, but beyond this indicator may lead to bleeding, so it is important to follow the doctor’s advice and go to the hospital regularly to review the relevant indicators.