Thalassemia alpha 4.2 Treatment should be tailored to the severity of the disease, and is generally not required for the mild and quiescent forms, but is required for the intermediate and severe forms. Treatment includes general treatment, blood transfusion and iron removal treatment, iron chelator treatment and surgical treatment. 1. General treatment: pay attention to rest, maintain adequate nutrition, and actively prevent infection. Supplement folic acid and vitamin E as appropriate. 2. Blood transfusion and iron removal treatment: when thalassemia major can cause severe anemia or hemolytic crisis, timely and effective blood transfusion is needed, but blood transfusion can cause iron overload, so iron chelating agent (Deferasirox) should be given at the same time to promote iron excretion. Iron chelators also include desferrioxamine, which can increase iron excretion from urine and feces, preventing iron overload in the body, and the combined application of vitamin C and chelators can enhance the effect of desferrioxamine in iron excretion from urine. 3. Surgical treatment: If conservative treatment is ineffective, severe anemia, accompanied by splenomegaly and other symptoms, splenectomy can be treated. If there are conditions, hematopoietic stem cell transplantation treatment is also available. Thalassemia alpha type 4.2 treatment varies according to the severity of the disease. In general, the disease is well controlled after active treatment. It is recommended to visit a hospital in time to choose an appropriate treatment plan. All of the above medications should be used under medical supervision.