Low average red blood cell hemoglobin is most commonly associated with two diseases, one is iron deficiency anemia: for the treatment of iron deficiency anemia, the first step is to give iron supplementation therapy, and the commonly used iron supplementation drugs are two-dimensional ferrous iron, three-dimensional ferrous iron, iron dextran, ferrous lactate, ferrous fumarate and so on. However, iron supplements in general have obvious digestive side effects, and if the patient cannot tolerate them or if they are poorly absorbed in the intestine, they can also be treated with intravenous iron supplements, and the commonly used drug is iron sucrose. There is no cure for thalassemia because the disease is a genetic disorder. Secondly, thalassemia: if it is a mild form of thalassemia, it usually does not require treatment. However, if it is thalassemia major, it usually requires frequent blood transfusion treatment. Also pay attention to rest in daily life and avoid infection to prevent aggravation of the disease.