Pleural malignant nodule is a kind of malignant pleural tumor, pleural malignant tumor includes pleural primary tumor and secondary tumor. Most of the secondary pleural tumors originate from the lung and breast, and are pleural metastases, indicating that the disease is in an advanced stage and cannot be cured. Primary malignant tumors of the pleura are relatively rare and have a poor prognosis. The main treatment for secondary pleural tumors is to treat the primary lesion, which needs to be combined with TNM staging and the pathological nature of the primary lesion to decide the treatment plan, such as surgical treatment, radiotherapy, targeted therapy, immunotherapy, etc. Standardized treatment under the guidance of professional doctors can improve the quality of life and prolong the survival time. Primary tumors of pleura are rare, such as pleural mesenchymal tumors are divided into diffuse and limited, limited is generally benign, diffuse mesenchymal tumors are tumors with higher degree of malignancy, extensive lesions, extremely rapid progression of the disease, poor prognosis and poor therapeutic effect. If it is identified as malignant pleural nodule, it is necessary to go to the hospital in time for examination and avoid carelessness, so as not to delay the treatment.