According to the circadian fluctuations of the disease, choose the best time to take drugs to achieve the best results. 1, iron: anemia patients taking iron at 7 p.m., the concentration of iron in the blood is four times higher than when taken at 7 a.m., the best efficacy. 2, calcium: the human blood calcium level is lowest from midnight to early morning. Therefore, taking calcium before going to bed can make calcium fully absorbed and utilized. 3, blood pressure drugs: according to the rhythm of the human biological clock, blood pressure drugs, respectively, at 7:00 a.m., 3:00 p.m. and 7:00 p.m. three times, the morning and evening dosage than the afternoon dosage to be appropriate less. It is not advisable to take antihypertensive drugs before going to bed at night to prevent low blood pressure and bradycardia, resulting in cerebral thrombosis. 4, antibacterial and anti-inflammatory drugs: antibacterial drugs are excreted quickly, in order to maintain a certain concentration in the blood, every 6 hours should be taken once. Patients with rheumatic or rheumatoid arthritis, mostly in the early morning and morning joint pain is heavier, such as taking anti-inflammatory and painkilling drugs, can increase the dose in the morning to take a dose, the best effect, and can avoid the noon dose. 5, hypoglycemic drugs: diabetic patients are most sensitive to insulin in the early morning, when the insulin injection dosage is small, the effect is good. 6, cardiac drugs: cardiac patients are most sensitive to digitalis, digoxin, and Westland, etc. 7, anti-asthma drugs: aminophylline should be taken at about 7 a.m., the best effect. 8, anti-allergy drugs: Cyproheptadine taken at about 7 a.m., can make the effect of 15 to 17 hours, and 7 p.m., can only last 6 to 8 hours. 9, hormonal drugs: the body’s response to hormonal drugs also has a time rhythm. As the human adrenal cortex, the peak of hormone secretion at about 7:00 a.m., so the best efficacy is given at once at 7:00 a.m. every day. 10, antipyretic and analgesic drugs: such as aspirin, taken at about 7:00 a.m. (after a meal) is highly effective and long-lasting, if taken at 6:00 p.m. and 10:00 p.m., the effect is poor. 11, cholesterol-lowering drugs: because the production of cholesterol and other blood lipids in the human body at night will 12, hypnotic drugs, deworming drugs, birth control pills: it is generally advisable to take half an hour before going to bed at night.