Anterior lumbar 5 vertebral body slippage may be due to degeneration and laxity of the myofascial ligaments in the back, posterior lateral pedicle rupture due to trauma, or congenital isthmic fracture, which can lead to instability in the lumbar spine area. 1. Myofascial ligament laxity: due to the natural degeneration of the lumbar spine, long-term chronic injury and inflammatory stimulation, the ligament elasticity decreases, resulting in anterior slip of the lumbar 5 vertebrae. 2. Posterior lateral vertebral arch rupture: Due to sports such as gymnastics, weight lifting and soccer, the vertebral bodies of the spine and vertebral arches are often subjected to repeated stress. The continuous hyperextension of the lumbar region during exercise can also cause a rupture of the vertebral arch, leading to anterior slip of the lumbar 5 vertebrae. 3. Congenital isthmic cleft: If the patient has congenital structural defects such as cartilage defects, incomplete ossification, etc., which can result in congenital isthmic bone non-connection, or poor development here, it can also lead to lumbar 5 anterior vertebral body slippage. If the patient’s lumbar 5 anterior vertebral body slippage is serious, or if the symptoms continue to fail to improve, the patient should go to the hospital for timely diagnosis and standardized treatment.