Men with pain in urination need to be further examined to clarify the cause of the disease and then given symptomatic pain medication.1. If a urinary tract infection occurs, with obvious urinary frequency and urgency, accompanied by pain in the urethra during urination, it is recommended to orally take Levofloxacin Hydrochloride capsule, 1 capsule, 3 times a day. Oral diclofenac sodium capsule, 1 capsule, once a day, 3 consecutive days of oral intake, to observe whether the pain is relieved; 2, if the pain of urination caused by trauma, such as the impact injury of the penis or the perineal area riding straddle injuries during the fall, the pain of urination, then consider related to trauma. Further urethroscopy or urethrography is recommended to clarify the degree of damage. If the damage is slight, take oral diclofenac sodium capsule, one capsule, once daily, and cefixime capsule, one capsule, twice daily, and observe whether the pain is relieved. However, if there is a urethral contusion or fracture, surgical repair is needed; 3. If there are stones in the urethra, they can cause pain during urination with difficulty in urination. It is recommended to take oral anti-inflammatory and analgesic drugs to relieve pain after removing the stones. Generally, the pain can be gradually reduced or disappear after the stones are discharged.