On January 7, 2021, the official website of the National Health Commission released the announcement of “Three New Foods”, and HAPLEXPlus Sodium Hyaluronate was approved as a new food ingredient, which can be used in general food additives. Subsequently, HAPLEXPlus launched two hyaluronic acid food products, one is hyaluronic acid sugar and the other is hyaluronic acid water. Hyaluronic acid is an acidic mucopolysaccharide, which was first isolated from the vitreous humor of the cow’s eye in 1934 by Meyer et al, professor of ophthalmology at Columbia University. Hyaluronic acid with its unique molecular structure and physicochemical properties in the body shows a variety of important physiological functions, such as lubrication of joints, regulating the permeability of blood vessel walls, regulating proteins, water-electrolyte diffusion and operation, and promote wound healing. Hyaluronic acid itself is a polysaccharide, glucuronic acid and glucosamine two monosaccharides combined. The scientific name is hyaluronic acid, its 08 years through the approval, can be used for health food. Pharmaceutical and food grade can be eaten, cosmetic grade hyaluronic acid can not be eaten. Hyaluronic acid originally exists in the skin, can help the skin from the body and the skin surface layer to absorb water, but also can enhance the skin’s ability to retain water for a long time. When hyaluronic acid absorbs water, making elastic fibers and collagen in a moist environment, the skin therefore has the elasticity. However, skin hyaluronic acid from the age of 25 years later began to lose, at the age of 30 years old, only 65% of the remaining juvenile, 60 years old, only 25% of the remaining, the skin’s moisture will be followed by hyaluronic acid and loss of elasticity and luster, and in the long run, the aging phenomenon of wrinkles. Hyaluronic acid is a long chain of macromolecules, can not pass through the skin and reach the dermis, so wipe hyaluronic acid wrinkles is impossible, but hyaluronic acid is a good water retention component, after the use of the skin can reduce the dryness of the small fine lines caused by the skin, so a certain degree of coated hyaluronic acid is useful. But can the hyaluronic acid eaten still hydrate the skin?In 2016, there was a paper, “Oral hyaluronic acid on skin moisture improvement and in vivo antioxidant effect of the study” which pointed out that oral hyaluronic acid can hydrate, but the paper is Huaxi Biological and Shandong University School of Pharmacy jointly, and hyaluronic acid food is Huaxi Biological production. I personally think that hyaluronic acid food can not be absorbed by the skin, into the digestive system will be decomposed, playing into the prototype of hyaluronic acid can not be re-grouped back to the prototype, lack of theoretical basis. Of course, this is also my personal deduction, the specific has no effect.