Empty follicles are follicles that do not have eggs, and empty follicles occur due to the lack of synchronization between the time of death of the egg cell and the follicular cell. Empty follicles can’t be fertilized normally, so they can’t be conceived. Occasionally, empty follicles won’t affect the normal function of pregnancy, but long-term empty follicles are likely to affect the ovarian function, and there is a risk of premature aging or even infertility. Clinically, medication can be taken, as the occurrence of empty follicles is related to the body’s hormone levels or ovarian function, can be adjusted by taking hormone drugs or drugs to promote ovulation can make the follicles return to normal, will not have an impact on pregnancy. It is recommended that women who want to get pregnant pay attention to the observation of ovulation and ovulation cycle, if necessary, sex hormone six and ovarian function test.