Olanzapine belongs to the class of sedative sleeping drugs, usually the principle of treatment of poisoning of the above drugs should be immediately gastric lavage, gastric lavage treatment is the most effective means of treatment within 8 hours after taking the drug, if at this time conscious, give vomiting picking the throat for gastric lavage, but the vast majority of patients at this time are unconscious, coma, lethargy, it is necessary to give the intubation gastric lavage way. Gastric lavage fluid should be selected saline, the amount of gastric lavage fluid should be selected in more than 10,000ml, try to gastric lavage fluid for colorless, clarified, tasteless, proving the success of gastric lavage, gastric lavage can be given to mannitol or activated charcoal adsorption, enema, severe cases should also be given to continuous blood purification way of treatment.