Nodules in the shoulder and neck are usually due to muscle strain in the cervical spine or shoulder, and over time, local aseptic inflammation occurs, and the formation of local inflammatory nodules occurs. It may also be caused by cervical spondylosis, where degenerative changes in the cervical spine compress the nerve roots, resulting in pulling pain in the nerves and long-term muscle tension, which over time can also lead to local aseptic inflammation, resulting in the formation of nodules. Inflammatory nodules of the muscle, when pressed, will appear very obvious pain, which can be slowly relieved by local physical therapy such as massage, massage or topical ointment. However, it is important to note that if the nodule is localized and not painful, it may be caused by other reasons. The most common ones are subcutaneous masses such as sebaceous cysts, fibroids, and lipomas. It is basically possible to identify them by local ultrasound.