Whether taking amoxicillin for stomach pain is useful or not needs to be determined based on the specific condition and the individual’s constitution. If the abdominal pain is caused by Helicobacter pylori infection, it is useful for treatment. Amoxicillin is an antibiotic for infections caused by Escherichia coli, Streptococcus pneumoniae and others. Abdominal pain is mainly considered for digestive disorders, and oral amoxicillin is usually ineffective for non-infectious digestive disorders; in the case of inflammation or ulcers in the digestive system caused by H. pylori infection, oral amoxicillin is useful but needs to be used in conjunction with other medications. Amoxicillin may have adverse reactions such as diarrhea, black tongue, itchy skin, anemia, and insomnia. Amoxicillin is contraindicated in people who develop severe allergies to amoxicillin or other beta-lactam antibiotics, such as penicillin and cephalosporins. Also oral contraceptives may reduce the effectiveness of contraception. Amoxicillin should not be abused to avoid the development of drug resistance. The above medications should be administered under the supervision of a physician. If the patient’s abdominal pain symptoms are severe or the symptoms persist for several days without improvement, the patient should go to the hospital in time for treatment.