High red blood cells in the urine routine usually indicates that the patient has hematuria, which may be caused by physiological reasons such as strenuous exercise, or pathological reasons such as urological diseases, common glomerular diseases, urinary stones, renal tumors, and non-urinary diseases such as septicemia, epidemic hemorrhagic fever and so on. 1. Physiological causes: normal people who usually have less exercise may have exercise hematuria after suddenly increasing the amount of exercise, resulting in high red blood cells in the urine routine, but this is only transient and does not require special treatment. 2. Pathologic causes: (1) Urological diseases: such as glomerular diseases, most of which are manifested by hematuria, proteinuria, hypertension and edema; when renal stones or ureteral stones are present, the friction of stones on the mucous membrane leads to mucous membrane hemorrhage and then hematuria; renal tumors also cause painless hematuria of the naked eye when invading calyxes and renal pelvis. (2) Non-urinary diseases: sepsis, epidemic hemorrhagic fever, leukemia, aplastic anemia, etc. may also cause increased red blood cells in urine routine. There may be other reasons for the high red blood cells in urine routine, it is recommended that the patient timely to the regular hospital, improve the examination to clarify the cause of the disease, under the guidance of the doctor to targeted treatment or therapy.