Calcification of pulmonary nodules is a description of the density of nodules in the lungs by ct examination, which can be analyzed according to the different forms of calcification combined with the condition of the nodule to analyze the benign or malignant nature of the lesion. Clinically, soft tissue lesions less than 3 cm in size are diagnosed as nodules, and obvious dense shadows found in the nodules suggest calcification of the lung nodules. Different calcification conditions in the nodules have a certain guiding role in determining the benign or malignant nature. Generally speaking, coarse, granular calcifications are mostly benign; fuzzy, gravelly calcifications may be malignant. It is necessary to determine whether the nodule is accompanied by malignant signs such as irregular morphology, irregular margins, visible burrs, lobulation, vascular clustering, vacuoles, and pleural pulling to further diagnose the status of the nodule. Highly suspicious malignant lesions require puncture biopsy if necessary. After the diagnosis of lesions should be standardized treatment under the guidance of the clinician, do not use drugs privately, so as not to cause harm to the body.