There is no cause-specific treatment for Hashimoto’s thyroiditis. Clinical treatment focuses on symptoms of hypothyroidism and goiter compression, which may be treated medically or surgically. Limiting iodine intake may help to stop the progression of autoimmune destruction of the thyroid. People with goiter only and no hypothyroidism generally do not require treatment. Levothyroxine replacement therapy is given primarily for clinical or subclinical hypothyroidism. Glucocorticoid therapy may be given when the thyroid gland is rapidly enlarging with localized pain or pressure symptoms. Surgery may be considered for those who have obvious compression symptoms that are not relieved by medication, but the probability of postoperative hypothyroidism is high with surgical treatment. Hashimoto’s thyroiditis patients must be timely medical treatment for comprehensive treatment, and regular review of thyroid function, so as not to delay the condition.