Clinically, for liver cancer that can be diagnosed through history, imaging and AFP examination, there is no need for puncture biopsy before radiofrequency; for liver cancer that is difficult to be diagnosed clearly, local puncture biopsy is needed before radiofrequency ablation to make a clear diagnosis, and it can be performed only when it is determined to be liver cancer. Liver cancer needs to be clearly diagnosed as liver cancer before radiofrequency ablation of liver cancer, and liver biopsy is needed for atypical and uncertain cases. Before radiofrequency ablation for hepatocellular carcinoma, relevant examinations need to be perfected, first of all, the location of the tumor needs to be determined by imaging examination, so as to make an advance planning for the surgical plan and prevent damage to large blood vessels or bile ducts. At the same time, it is also necessary to evaluate the cardiopulmonary function of the patient and improve the examination of liver function and blood coagulation function. Radiofrequency ablation of liver cancer should be evaluated on the actual condition of the patient, not all liver cancer patients can undergo radiofrequency ablation, and need to be actively treated under the guidance of doctors.