Generally, common cold symptoms are mild and dominated by upper respiratory tract symptoms; new coronavirus infections may be characterized by fever, malaise, dry cough, and so on. Most common colds are also caused by viral infections, and are usually characterized by localized upper respiratory tract symptoms, such as runny nose, nasal congestion, sore throat, etc., and generally rarely cause clinical symptoms such as general malaise and fever. Symptoms caused by the new coronavirus may be similar to those of a cold in the early stages, and in the later stages, nasal congestion, runny nose, sore throat, decreased or loss of smell and taste, conjunctivitis, myalgia, and diarrhea may appear as the main manifestations. In severe cases, respiratory distress and/or hypoxemia may occur one week after the onset of the disease, and in severe cases, acute respiratory distress syndrome, uncorrectable metabolic acidosis, and multi-organ failure may occur rapidly, and the progression of neocoronaviral infection is generally faster than that of the common cold. When respiratory symptoms, fever and other discomforts occur, it is recommended to seek immediate medical attention.