The baby’s fever of 39 ℃ after vaccination is already high, it should be considered that the body produces vaccination reaction after vaccination, the immunity is temporarily reduced, secondary viral or bacterial infection. So the treatment should be: first, immediately oral antipyretic drugs, such as ibuprofen, acetaminophen, after eating antipyretic drugs to drink more water, to help reduce fever; second, can be used to paste the cooling patch, take a warm bath and other physical cooling methods to reduce fever; third, the cause of the fever should be directed to the cause of the treatment, if it is a viral infection, you can usually take the clearing of heat and detoxification, anti-virus class of proprietary Chinese medicines, such as antiviral oral liquid treatment If there is a bacterial infection, usually need oral antibiotics, commonly used cefaclor, amoxicillin, etc.; Fourth, pay attention to good dietary management, should be a small number of meals, avoid greasy stimulating food intake, so as not to aggravate the digestive tract or other clinical symptoms.