Taking entecavir is not recommended for having children. Entecavir is used clinically primarily for the treatment of chronic adult hepatitis B with persistent elevation of serum aminotransferase ALT or liver histology showing active lesions with active viral replication. However, because clinical studies of the effects on pregnant women are insufficient, entecavir may be used as prescribed by the physician after fully weighing the potential risk benefit to the fetus, and it is generally not recommended to have children while taking the drug. At the same time, there is no clear information that the drug affects mother-to-child transmission of HBV, so appropriate interventions should be taken in a timely manner to avoid neonatal infection with HBV. and for the drug will be secreted in human breast milk, is not known, is generally not recommended to breastfeeding women, to prevent the existence of potential harm. It is recommended that patients take entecavir strictly in accordance with medical advice, and under the guidance of the doctor to arrange the time of preparation for pregnancy, in order to avoid adverse effects on the fetus.