The pain in the heart after meals is mostly considered to be caused by angina pectoris due to coronary artery atheromatous heart disease, but also due to peptic ulcer, gastroesophageal reflux disease and other causes. 1. Angina pectoris of coronary artery atheromatous heart disease: it can be induced by meal, due to eating increased myocardial oxygen consumption, resulting in myocardial oxygen demand is greater than the supply of oxygen, resulting in myocardial ischemia, patients with angina pectoris symptoms, there can be postprandial pain in the fossa of the heart performance, accompanied by other symptoms, such as profuse sweating, chest tightness, shortness of breath, etc., to do electrocardiography and other tests can be diagnosed with this disease. 2. Peptic ulcer: mainly gastric ulcer is common, gastric ulcer abdominal pain pattern is mostly postprandial epigastric pain, after digestion to relieve, so postprandial pain may be gastric ulcer patients after eating, causing epigastric pain, accompanied by other symptoms, such as acid reflux, bloating and so on. 3. Gastroesophageal Reflux Disease (GERD): Food reflux into the esophagus after eating can cause pain in the back of the sternum and the lower part of the xiphoid process, mostly burning pain. It is recommended to consult the hospital for the pain in the heart’s mouth fossa after meals. Identify the cause of the disease and take targeted treatment under the guidance of the doctor.