Pain at the back of the big teeth, if the pain is at the very end of the tooth bed, is usually due to wisdom tooth pericoronitis, mainly due to the presence of wisdom teeth in the mouth, and most of them are blocked wisdom teeth. Wisdom teeth are surrounded by blind pockets in the gums, where a large amount of bacteria and food debris can be deposited. When the body’s immune function is low, such as colds and fevers or travel fatigue, it is easy to cause inflammation of the gums and soft tissues around the wisdom teeth, resulting in pain at the very end of the bed of the teeth, and in severe cases, it may even cause a series of systemic symptoms, such as facial swelling, limited opening of the mouth, enlarged lymph nodes in the lower jaw, and even a low-grade fever. In this case, the first thing to do is to use a sufficient amount of antibiotics anti-inflammatory, such as oral cephalosporin and metronidazole tablets for combined anti-inflammatory, the symptoms of obvious people can be used intravenous infusion method for anti-inflammatory treatment. When the inflammation is fully controlled and the symptoms are completely relieved, it is recommended to remove the blocked wisdom teeth as soon as possible to prevent the recurrence of wisdom teeth pericoronitis.