Goosebumps on the hands may be herpes sweat, frictional lichen planus and other diseases. 1. Sweat herpes: blistering skin disease that occurs in the palm and plantar area. Sweat herpes symptoms for deep in the small blisters, corn grain to rice size, slightly above the skin surface, often without redness. Symmetrically occurring in the palm and plantar and fingers (toes) side. 1 ~ 2 weeks after the drying and flaking, and can recur, with varying degrees of burning and itching, often continuous episodes for several years. The treatment of sweaty herpes: for patients with sweaty hands and feet, anticholinergic drugs such as atropine can be used, and glucocorticosteroid therapy can be used in severe cases, such as oral prednisone. 2. Frictional mossy rash: often occurs in the friction part of the easily irritated, skin lesions for the size of corn grain flat or hemispherical papules, often dense piece, but not fusion, covered with fine chaff-like scales, was mildly mossy, inflammation is slight. Generally normal skin color, the more severe may be light red. There are usually no self-conscious symptoms, sometimes mild itching sensation. The disease is self-limiting. If treatment is needed, usually only symptomatic treatment is needed, such as topical glycerite lotion. If the condition of goose bumps on the hands is not relieved, it is recommended to consult a doctor in a timely manner, to clarify the cause of the disease under the guidance of the doctor to standardize the treatment, the use of drugs need to follow the doctor’s instructions, to avoid self-medication.