Patients: First, May 18-June 20 during the treatment of otitis media and rhinitis, there are oxyfloxacin ear drops, and nasal drops; Second, June 22-July 10 because of itching at the calf, the doctor said it is eczema, after taking the medicine is better, but the old doctor prescribed the kind of medicine in bulk, do not know what kind of medicine, round a piece of the kind, a total of five, ten days of medicine; Third, July 8 or so Some cold, no fever, after taking some cold medicine (seems to be amoxicillin); during this period my wife everything is normal; my wife recently had her period this time on July 26, and in August my wife got pregnant. We want to keep this baby, what tests should be done in conjunction? I look forward to your help to reply, thank you! Doctor: Hello, the baby is not affected by your medication for two reasons: first, the time of medication is long before conception, far beyond the half-life of the drug; second, the effect of early conception is “all or nothing”, since the baby is healthy and survived, it means that the drug has no effect. However, there are many factors that affect pregnancy, and the existence of other high-risk factors cannot be excluded, therefore, it is recommended that the hospital establish regular checks, ultrasound screening for large malformations (high-risk ultrasound) is the first test to be considered, except for fetal malformations, good luck!