Endometrial cancer is a group of epithelial malignant tumors occurring in the endometrium, with adenocarcinoma originating from endometrial glands being the most common. It is one of the three major malignant tumors of female reproductive tract, accounting for 7% of systemic malignant tumors and 20%-30% of malignant of female reproductive tract. The average age of onset is 60 years old, of which 75% occurs in women over 50 years old. The etiology of endometrial cancer is not well understood. Two types of endometrial cancer are usually classified; type I is estrogen-dependent, which may occur as a result of endometrial hyperplasia, atypical hyperplasia, in the presence of prolonged action of estrogen without progesterone antagonism. Endometrial hyperplasia is mainly divided into two categories: without atypical hyperplasia and atypical hyperplasia, the former is a benign lesion, and the latter is a pre-cancerous lesion, which may develop into cancer. endometrial carcinoma of type I is most common, and the patients are relatively young, often accompanied by obesity, hypertension, diabetes mellitus, infertility or infertility, and delayed menopause, or accompanied by a history of anovulatory disorders, functional ovarian tumors, and long-term use of monoestrogens or tamoxifen, and etc. The prognosis is better. The prognosis is better. Type II endometrial cancer is non-estrogen-dependent, with no clear relationship between the onset and estrogen. It is most common in elderly women, and atrophic endometrium can be found around the cancer foci. The tumor is highly malignant, poorly differentiated and has a poor prognosis. Most endometrial cancers are sporadic, but about 5% are genetically related, and the most closely related genetic syndrome is Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer syndrome, an autosomal dominant disorder associated with the development of endometrial cancer in young women.